(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
- CAS No.: 209414-27-7
- Purity: 99%
Quality products?make an important contribution to long-term revenue and profitability. High quality purity >99% (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol 209414-27-7 for sale
1.What is the (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol ?
Intermediate in the preparation of Efavirenz (E425000) impurity.
-
-
6746-94-7
Cyclopropylacetylene
-
-
154598-53-5
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone
-
-
209414-27-7,927812-33-7,154598-58-0
(2S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
| Conditions | Yield |
|---|---|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
96%
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
95%
|
|
With
2-dibenzyalamino-1-phenyl-1-propanol; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
95%
|
|
Cyclopropylacetylene;
With
methanesulfonic acid sodium salt; sodium hydride; zinc(II) chloride;
In
tetrahydrofuran;
at -5 - 0 ℃;
for 4h;
With
2,2,2-trifluoroethanol; sodium hydride; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol;
at 10 ℃;
for 1 - 2h;
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
ammonium chloride;
at 10 ℃;
for 3h;
Concentration;
Reagent/catalyst;
|
95%
|
|
With
dimethyl zinc(II); 2-methylamino-1-phenylpropanol;
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
94%
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
tetrahydrofuran; toluene;
at -20 - 0 ℃;
With
2,2-dimethyl-propanol-1;
In
tetrahydrofuran; toluene;
at 20 - 60 ℃;
for 1.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
94%
|
|
Cyclopropylacetylene;
With
butyl magnesium bromide;
In
tetrahydrofuran;
at 5 - 10 ℃;
for 2h;
Large scale;
With
sodium;
In
tetrahydrofuran; 2,2,2-trifluoroethanol;
at 10 - 25 ℃;
for 1h;
Inert atmosphere;
Large scale;
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
Further stages;
Large scale;
|
93%
|
|
With
dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
90%
|
|
With
2-dimethylamino-1-phenyl-propan-1-ol; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
90%
|
|
Cyclopropylacetylene;
diethylzinc; (1S,2R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol; (S)-(-)-2,4-diphenylbut-3-yn-2-ol;
In
tetrahydrofuran; toluene;
at 15 - 20 ℃;
for 1.5h;
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-hexyllithium;
In
tetrahydrofuran; hexane; toluene;
at -5 - 40 ℃;
for 11h;
With
citric acid;
In
tetrahydrofuran; hexachloroethane; water; toluene;
pH=4 - 6;
Product distribution / selectivity;
|
87%
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
83%
|
|
With
methanol; dimethyl zinc(II);
In
toluene;
at -78 - 20 ℃;
for 1h;
With
(1R,2S)-N-pyrrolidinyl norephedrine;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
83%
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butylmagnesium iodide;
more than 3 stages;
Product distribution / selectivity;
|
76.6%
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; 2,2,2-trifluoroethanol; diethylzinc;
In
tetrahydrofuran;
at 0 - 30 ℃;
for 0.5 - 1h;
Cyclopropylacetylene;
With
butyl magnesium bromide;
In
tetrahydrofuran;
at 0 - 30 ℃;
for 0.666667 - 2h;
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
In
tetrahydrofuran;
at -8 - 28 ℃;
for 3.5 - 38h;
|
74%
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; 2,2,2-trifluoroethanol; diethylzinc;
In
tetrahydrofuran;
at 0 - 30 ℃;
for 0.5 - 1h;
Cyclopropylacetylene;
With
n-butyllithium;
In
tetrahydrofuran;
at 0 - 30 ℃;
for 0.666667 - 2h;
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
In
tetrahydrofuran;
at -8 - 28 ℃;
for 3.5 - 38h;
|
74%
|
|
Cyclopropylacetylene;
With
diethylzinc; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol;
In
tetrahydrofuran; toluene;
at 15 - 20 ℃;
Inert atmosphere;
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-hexyllithium;
In
tetrahydrofuran; hexane; toluene;
at 0 - 40 ℃;
optical yield given as %ee;
enantioselective reaction;
Inert atmosphere;
|
67%
|
|
With
(1R,2R)-pseudoephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
63.3%
|
|
With
Δ-Ru1; triethylamine;
In
tetrahydrofuran;
at 60 ℃;
for 48h;
enantioselective reaction;
Inert atmosphere;
Schlenk technique;
Sealed tube;
|
58%
|
|
With
Δ-Ru1; triethylamine;
In
tetrahydrofuran;
at 60 ℃;
for 48h;
enantioselective reaction;
Inert atmosphere;
|
58%
|
|
With
diphenyl(pyrrolidin-2-yl)methanol; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
30%
|
|
With
(1S,2S)-N-Methylpseudoephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
28.6%
|
|
With
Diethyl tartrate; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
26.2%
|
|
With
norepinephrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
methanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
25.5%
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; 2,2,2-trifluoroethanol; diethylzinc; butyl magnesium bromide;
Yield given;
Multistep reaction;
1.) THF, 0 deg C, 1 h, 2.) THF, toluene, 0 deg C, 15 h;
|
|
|
With
(1S,2S)-N-Methylpseudoephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
2,2-dimethyl-propanol-1;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
65.8 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
isopropyl alcohol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
69 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
trifluoroacetic acid;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
89.4 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
trifluoroacetic acid;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
76.2 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
allyl alcohol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
90 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
benzyl alcohol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
89 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
ethanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
more than 3 stages;
Product distribution / selectivity;
|
55 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
tert-butyl alcohol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
89.8 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
1,1,1-trichloroethanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
96 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
3,3-dimethyl-2-butanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
89 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
acetic acid;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
82 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
Trimethylacetic acid;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
71.6 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
2,2-dimethyl-propanol-1;
In
toluene;
at 40 ℃;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
94 - 95.6 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
2-(N,N-dimethylamino)ethanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
78.2 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
2,2,2-trifluoroethanol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
95.7 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
4-nitro-phenol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
89 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc(II);
In
toluene;
for 1h;
With
triphenylmethyl alcohol;
In
toluene;
for 0.5h;
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
butyl magnesium bromide;
more than 3 stages;
Product distribution / selectivity;
|
74.4 % ee
|
|
With
(1R,2S)-N-pyrrolidinyl norephedrine; n-hexyllithium;
diethylzinc;
In
tetrahydrofuran; toluene;
at 0 - 40 ℃;
Product distribution / selectivity;
Inert atmosphere;
|
97.16 % ee
|
|
Cyclopropylacetylene; 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
diethylzinc; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol;
In
tetrahydrofuran; toluene;
at 0 - 30 ℃;
With
water; citric acid;
In
tetrahydrofuran; toluene;
at 20 ℃;
With
sodium hydrogencarbonate;
In
tetrahydrofuran; water; toluene;
|
94 % ee
|
|
Cyclopropylacetylene;
diethylzinc; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol;
In
tetrahydrofuran; toluene;
at 15 - 20 ℃;
for 1h;
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
In
tetrahydrofuran; toluene;
at 0 - 30 ℃;
With
citric acid;
In
tetrahydrofuran; water; toluene;
at 20 ℃;
for 0.25h;
|
|
|
Cyclopropylacetylene;
With
diethylzinc; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol;
In
tetrahydrofuran; toluene;
at 15 - 20 ℃;
for 1h;
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
In
tetrahydrofuran; toluene;
at 0 - 30 ℃;
|
99.6 % ee
|
|
Cyclopropylacetylene;
With
diethylzinc; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol;
In
tetrahydrofuran; toluene;
at 15 - 20 ℃;
for 1h;
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
In
tetrahydrofuran; toluene;
at 0 - 30 ℃;
|
99.6 % ee
|
|
Cyclopropylacetylene;
With
diethylzinc; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol;
In
tetrahydrofuran; toluene;
at 15 - 20 ℃;
for 1.5h;
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone;
With
n-butyllithium;
In
tetrahydrofuran; toluene;
at 20 - 30 ℃;
|
-
-
75-89-8
2,2,2-trifluoroethanol
-
-
6746-94-7
Cyclopropylacetylene
-
-
195372-65-7
N-(2-bromo-4-chlorophenyl)pivalamide
-
-
209414-27-7,927812-33-7,154598-58-0
(2S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
| Conditions | Yield |
|---|---|
|
2,2,2-trifluoroethanol;
With
sodium hydride;
In
toluene;
at 0 - 20 ℃;
for 1h;
With
zinc(II) chloride;
In
toluene;
at 0 - 20 ℃;
for 1h;
Cyclopropylacetylene; N-(2-bromo-4-chlorophenyl)pivalamide;
Further stages;
|
90%
|
2.What is the CAS number for (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol ?
The CAS number of (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol is 209414-27-7.
More information of (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol 209414-27-7 are:
|
CAS?Number |
209414-27-7 |
|
Density |
1.462 g/cm3 |
|
Boiling Point |
425.052 °C at 760 mmHg |
|
Flash Point |
210.864 °C |
|
Vapor Pressure |
0mmHg at 25°C |
|
Refractive Index |
1.575 |
|
HS CODE |
2922199695 |
|
PSA |
46.25000 |
|
LogP |
3.66670 |
|
Pka |
9.13±0.24(Predicted) |
3.What are another words for (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol ?
Synonyms?for?(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol 209414-27-7:Benzenemethanol,2-amino-5-chloro-a-(cyclopropylethynyl)-a-(trifluoromethyl)-, (aS)- (9CI);(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol;(aS)-2-Amino-5-chloro-a-(cyclopropylethynyl)-a-(trifluoromethyl)benzenemethanol;
4.What is the molecular formula of (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol?
The chemical formula of ?(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol is?C13H11ClF3NO which containing 13 Carbon atoms,11 Hydrogen atoms,1 Chlorine atoms,3 Fluorine atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol?is 289.685.
5.What is (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol (209414-27-7) used for?
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol is a complex organic compound characterized by its unique molecular structure. It is an off-white solid with specific chemical properties that make it a valuable intermediate in the synthesis of certain pharmaceutical compounds.
InChI:InChI=1/C13H11ClF3NO/c14-9-3-4-11(18)10(7-9)12(19,13(15,16)17)6-5-8-1-2-8/h3-4,7-8,19H,1-2,18H2/t12-/m0/s1
Relevant articles related to (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol:
|
Article |
Source |
|
Method for asymmetric synthesis of anti-Aids drug, namely efavirenz key intermediate |
- Paragraph 0017-0019, (2020/02/19) |
|
Synthetic method of efavirenz key intermediate |
- , (2019/01/08) |
6.Buy (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol with the best price .
Shanghai Sheng Zhan Chemical Technology Co., Ltd is a quality supplier of (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol 209414-27-7.
