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1.What is the TACRINE HYDROCHLORIDE ?
Pale Yellow Solid
Tacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively). Tacrine also inhibits the uptake of serotonin and norepinephrine in rat cerebral cortex and decreases depolarization-induced calcium influx through L-type calcium channels in SN56 neuronal cells. Formulations containing tacrine have been used clinically in the treatment of Alzheimer’s disease.
2.What is the CAS number for TACRINE HYDROCHLORIDE ?
The CAS number of TACRINE HYDROCHLORIDE is 1684-40-8.
3.What are another words for TACRINE HYDROCHLORIDE ?
Synonyms?for?TACRINE HYDROCHLORIDE 1684-40-8:9-Acridinamine,1,2,3,4-tetrahydro-, monohydrochloride (9CI);Acridine,9-amino-1,2,3,4-tetrahydro-, hydrochloride (7CI);9-Amino-1,2,3,4-Tetrahydroacridine hydrochloride;CI 970;Acridine,9-amino-1,2,3,4-tetrahydro-, monohydrochloride (8CI);1,2,3,4-Tetrahydro-9-aminoacridine hydrochloride;5,6,7,8-Tetrahydroacridin-9-amine hydrochloride;Cognex;Hydroaminacrine;Romotal;THA;Tacrin hydrochloride;Tacrine hydrochloride;Tenakrin;
4.What is TACRINE HYDROCHLORIDE (1684-40-8) used for?
A potent centrally acting anticholinesterase for therapy of memory deficits in patients with Alzheimer's disease. THA also selectively blocks potassium channels in the central nervous system, which results in an increased release of acetylcholine and a prolongation of the action potential of the presynaptic cholinergic neurons.
InChI:InChI=1/C13H14N2.ClH/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;/h1,3,5,7H,2,4,6,8H2,(H2,14,15);1H
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5.Buy TACRINE HYDROCHLORIDE with the best price .
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