Excellent chemical plant bulk supply 2-(2-NITROPHENYL)ETHANAMINE 33100-15-1
- Molecular Formula:C8H10 N2 O2
- Molecular Weight:166.18
- Boiling Point:147 °C(Press: 13 Torr)
- PKA:9.37±0.10(Predicted)
- PSA：71.84000
- Density:1.206±0.06 g/cm3(Predicted)
- LogP:2.31950
33100-15-1 Relevant articles
Substituted conformationally restricted guanidine derivatives: Probing the α2-adrenoceptors’ binding pocket
McMullan, Michela,García-Bea, Aintzane,Miranda-Azpiazu, Patricia,Callado, Luis F.,Rozas, Isabel
supporting information, p. 48 - 57 (2016/08/01)
In this paper we report the design, synt...
Design and synthesis of benzoazepin-2-one analogs as allosteric binders targeting the PIF pocket of PDK1
Wei, Linyi,Gao, Xiaoqi,Warne, Robert,Hao, Xueshi,Bussiere, Dirksen,Gu, Xiang-Ju,Uno, Tetsuo,Liu, Yi
scheme or table, p. 3897 - 3902 (2010/09/03)
A novel series of benzoazepin-2-ones wer...
Effect of potential amine prodrugs of selective neuronal nitric oxide synthase inhibitors on blood-brain barrier penetration
Silverman, Richard B.,Lawton, Graham R.,Ranaivo, Hantamalala Ralay,Chico, Laura K.,Seo, Jiwon,Watterson, D. Martin
experimental part, p. 7593 - 7603 (2011/02/23)
Several prodrug approaches were taken to...
CGRP receptor antagonists
-
Page/Page column 139, (2008/06/13)
The present invention relates to CGRP re...
33100-15-1 Process route
-
-
610-66-2
2-nitro-benzeneacetonitrile
-
-
33100-15-1
2-(2-aminoethyl)nitrobenzene
| Conditions | Yield |
|---|---|
|
2-nitro-benzeneacetonitrile;
With
dimethylsulfide borane complex;
In
tetrahydrofuran;
at 0 ℃;
for 8h;
Heating / reflux;
With
methanol;
for 1h;
Heating / reflux;
|
100% |
|
With
borane-THF;
at 0 - 20 ℃;
Inert atmosphere;
|
82% |
|
With
dimethylsulfide borane complex;
In
tetrahydrofuran;
at 0 - 70 ℃;
for 8h;
Inert atmosphere;
|
82% |
|
With
borane-THF;
|
-
-
33100-26-4
2-nitrophenethyl azide
-
-
33100-15-1
2-(2-aminoethyl)nitrobenzene
| Conditions | Yield |
|---|---|
|
2-nitrophenethyl azide;
With
triphenylphosphine; calcium carbonate;
In
benzene;
at 20 ℃;
With
hydrogen bromide;
In
water; acetic acid;
at 100 ℃;
for 1h;
|
|
|
2-nitrophenethyl azide;
With
triphenylphosphine; calcium carbonate;
In
benzene;
at 20 ℃;
With
hydrogen bromide; acetic acid;
In
water;
at 100 ℃;
for 1h;
With
sodium hydroxide;
In
water;
|
|
|
2-nitrophenethyl azide;
With
triphenylphosphine; calcium carbonate;
In
benzene;
at 20 ℃;
With
hydrogen bromide; acetic acid;
In
water;
at 100 ℃;
for 1h;
With
sodium hydroxide;
In
water;
|
33100-15-1 Upstream products
-
2001-32-3
3-(2-nitrophenyl)propionic acid
-
315663-43-5
N-(2-nitro-phenethyl)-acetamide
-
64-04-0
phenethylamine
-
16793-89-8
(2-bromoethyl)-2-nitrobenzene
33100-15-1 Downstream products
-
33100-17-3
N-Benzolsulfonyl-2-(2-nitrophenyl)-ethylamin
-
315663-43-5
N-(2-nitro-phenethyl)-acetamide
-
172505-78-1
1-[2-(2-Nitro-phenyl)-ethyl]-3-thiazol-2-yl-thiourea
-
168971-00-4
4-<5-(acetamidomethyl)furan-2-yl>-2-<<(2-aminophenyl)ethyl>guanidino>thiazole
